Sit and stay a while: how BfiSR controls irreversible attachment in Pseudomonas aeruginosa biofilms.

نویسنده

  • Andrew L Goodman
چکیده

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A Novel Signaling Network Essential for Regulating Pseudomonas aeruginosa Biofilm Development

The important human pathogen Pseudomonas aeruginosa has been linked to numerous biofilm-related chronic infections. Here, we demonstrate that biofilm formation following the transition to the surface attached lifestyle is regulated by three previously undescribed two-component systems: BfiSR (PA4196-4197) harboring an RpoD-like domain, an OmpR-like BfmSR (PA4101-4102), and MifSR (PA5511-5512) b...

متن کامل

SagS contributes to the motile-sessile switch and acts in concert with BfiSR to enable Pseudomonas aeruginosa biofilm formation.

The interaction of Pseudomonas aeruginosa with surfaces has been described as a two-stage process requiring distinct signaling events and the reciprocal modulation of small RNAs (sRNAs). However, little is known regarding the relationship between sRNA-modulating pathways active under planktonic or surface-associated growth conditions. Here, we demonstrate that SagS (PA2824), the cognate sensor ...

متن کامل

Do Not Fear Commitment: The Initial Transition to a Surface Lifestyle by Pseudomonads

This chapter aims to describe the early stages of biofilm formation, particularly on abiotic surfaces, by focusing on Pseudomonas aeruginosa. Specifically, we will dissect the early steps in the establishment of a multicellular community: (i) translocation to the surface from a free-swimming planktonic lifestyle, (ii) initial or reversible attachment, and finally (iii) irreversible attachment. ...

متن کامل

cAMP Signaling Affects Irreversible Attachment During Biofilm Formation by Pseudomonas aeruginosa PAO1

Pseudomonas aeruginosa responds to environmental changes and regulates its life cycle from planktonic to biofilm modes of growth. The control of cell attachment to surfaces is one of the critical processes that determine this transition. Environmental signals are typically relayed to the cytoplasm by second messenger systems. We here demonstrated that the second messenger, cAMP, regulated the a...

متن کامل

بیوفیلم پسودوموناس ایروژینوزا و روش‌های پیشگیری و درمان‌های تازه آن

  Background and Objective: Microbial biofilms are responsible for 65% of human infections, and are resistance to antibiotics. Pseudomonas aeruginosa is one of the most important biofilm producing bacteria. This review tries to explain the last mechanisms of Pseudomonas aeruginosa biofilm formation, the reasons for its resistance to antimicrobial agents, as well as new preventive measures and a...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Journal of bacteriology

دوره 192 20  شماره 

صفحات  -

تاریخ انتشار 2010